Papkov V G
Morfologiia. 1993 Jul-Aug;105(7-8):85-90.
A morphological investigation of the thymus was performed in 82 patients dead from rheumatism. The germinal centers of the thymus localized in the cortical layer and medullary substance were found in 42% of observations. These centers were not homogeneous in their structure. Some of them represent germinal centers of lymphoid nodules, others have epithelioreticulocytes. The latters having a substantial difference from the centers of the lymphoid nodules should be referred to as thymic islands. Necrosis of their cells appear in these islands, its spreading being responsible for transformation of the islands in cysts. The appearance of islands and the following necrosis are thought to be a mechanism of elimination of the thymus cells.
对82例死于风湿热的患者的胸腺进行了形态学研究。在42%的观察病例中,发现胸腺的生发中心位于皮质层和髓质。这些中心的结构并不均匀。其中一些代表淋巴小结的生发中心,另一些则有上皮网状细胞。与淋巴小结中心有显著差异的后者应称为胸腺岛。这些胸腺岛中出现细胞坏死,其扩散导致胸腺岛转变为囊肿。胸腺岛的出现及随后的坏死被认为是胸腺细胞清除的一种机制。