Yamamoto N, Kiyosawa M, Kawasaki T, Miki T, Fujino T, Tokoro T
Department of Ophthalmology, Tokyo Medical and Dental University, Japan.
J Neuroophthalmol. 1994 Jun;14(2):81-3.
A 45-year-old woman with adult T-cell leukemia had a sudden onset of decreased vision with central scotoma in the right eye. Right optic disc edema and thickening of the optic nerve were observed by magnetic resonance imaging. A diagnosis of leukemic infiltration to the optic nerve was made. A course of oral corticosteroid therapy was prescribed and 40 Gy of radiation was administered to the whole brain and right orbit. Her visual acuity recovered from finger counting to 20/20 within 3 weeks. We believe that this patient represents the first report of successfully treated optic nerve infiltration with adult T-cell leukemia caused by human T-lymphotropic virus type-I infection.
