Bibas P, Van Vooren J P, Schakal A, Deworme A, Dargent J L, Zanen A
Service d'Ophthalmologie, Hôpital Erasme, Université Libre de Bruxelles.
Bull Soc Belge Ophtalmol. 1993;250:67-76.
A patient with acquired immune deficiency and antecedents of pancreatitis presented with headaches, fever, dyspnea and bilateral decrease of vision. A diagnosis of disseminated cryptococcosis was made by lumbar puncture, alveolar washing and elevated cryptococcal antigen in blood, urine and stool. Bilateral chorioretinitis with ischaemic maculopathy was responsible of the low vision and attributed to cryptococcal infection after vitreous puncture and isolation of yeast from the vitreous. Systemic treatment with Amphotericin led to resolution of the chorioretinitis. A retinitis due to cytomegalovirus was associated short time before the patient died. Post-mortem anatomopathologic analysis revealed cryptococcus in high number in the choriocapillaris.
一名患有获得性免疫缺陷且有胰腺炎病史的患者出现头痛、发热、呼吸困难及双侧视力下降。通过腰椎穿刺、肺泡灌洗以及血液、尿液和粪便中隐球菌抗原升高，诊断为播散性隐球菌病。双侧脉络膜视网膜炎伴缺血性黄斑病变导致视力低下，在玻璃体穿刺并从玻璃体中分离出酵母后，归因于隐球菌感染。两性霉素全身治疗使脉络膜视网膜炎消退。在患者死亡前短时间内，出现了由巨细胞病毒引起的视网膜炎。尸检病理分析显示脉络膜毛细血管中有大量隐球菌。
