转基因小鼠的脂蛋白代谢与动脉粥样硬化易感性
Lipoprotein metabolism and atherosclerosis susceptibility in transgenic mice.
作者信息
Breslow J L
机构信息
Laboratory of Biochemical Genetics and Metabolism, Rockefeller University, New York.
出版信息
Curr Opin Lipidol. 1994 Jun;5(3):175-84. doi: 10.1097/00041433-199405030-00004.
Abstract
Lipoprotein transport genes have been used to make either transgenic or knockout mice with altered lipoprotein levels and metabolism. Either singly or in combination, these mice have provided new animal models of lipoprotein disorders and atherosclerosis.
摘要
脂蛋白转运基因已被用于制造脂蛋白水平和代谢发生改变的转基因小鼠或基因敲除小鼠。这些小鼠单独或联合使用，为脂蛋白紊乱和动脉粥样硬化提供了新的动物模型。
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