分子伴侣。打开和关闭安芬森笼。
Molecular chaperones. Opening and closing the Anfinsen cage.
作者信息
Ellis R J
机构信息
Department of Biological Sciences, University of Warwick, UK.
出版信息
Curr Biol. 1994 Jul 1;4(7):633-5. doi: 10.1016/s0960-9822(00)00140-8.
PMID:7953542
Abstract
Dynamic interactions between chaperonins allow newly synthesized polypeptides to begin correct folding inside a transiently closed cage. Specialized chaperonins may be used to deal with recalcitrant proteins.
摘要
伴侣蛋白之间的动态相互作用使新合成的多肽能够在一个短暂封闭的笼状结构内开始正确折叠。专门的伴侣蛋白可用于处理难折叠的蛋白质。
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