免疫缺陷疾病。ZAP-70的多重作用。
Immunodeficiency diseases. Multiple roles for ZAP-70.
作者信息
Hivroz C, Fischer A
机构信息
INSERM U 132, Hôpital Necker-Enfants Malades, Paris, France.
出版信息
Curr Biol. 1994 Aug 1;4(8):731-3. doi: 10.1016/s0960-9822(00)00162-7.
PMID:7953563
Abstract
Human patients with an immunodeficiency disease caused by mutations of the protein tyrosine kinase ZAP-70 show that this enzyme plays multiple important roles in T-cell differentiation and function.
摘要
因蛋白酪氨酸激酶ZAP-70突变而患有免疫缺陷疾病的人类患者表明，这种酶在T细胞分化和功能中发挥着多种重要作用。
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