Glickstein M
Department of Anatomy and Developmental Biology, University College, London, UK.
Brain. 1994 Oct;117 ( Pt 5):1209-12. doi: 10.1093/brain/117.5.1209.
Lesions of the cerebellum produce profound deficits in movement. Since there is demonstrable recovery from partial lesions, some have asserted that the cerebellum may not be necessary for normal movement. It is even alleged that people may not manifest any motor symptoms despite total cerebellar agenesis. The literature points to a different conclusion. Cerebellar agenesis is always associated with profound motor deficits. A case of cerebellar agenesis of a man who died in 1951 is discussed. Evidence is presented that it is this case which gave rise to part of the oral tradition which alleges that normal movement is possible despite total cerebellar agenesis. In this brain an MRI scan revealed a small residual cerebellum. Moreover, despite an oral tradition to the contrary, there is absolutely no evidence about the motor capacities of this man during his life.
小脑损伤会导致运动方面的严重缺陷。由于部分损伤后有明显的恢复情况,一些人断言小脑对于正常运动可能并非必需。甚至有人声称,即便小脑完全缺失,人们可能也不会表现出任何运动症状。但文献指向了不同的结论。小脑缺失总是与严重的运动缺陷相关。本文讨论了一名于1951年去世的男性小脑缺失病例。有证据表明,正是这个病例催生了部分口头流传的说法,即即便小脑完全缺失,正常运动仍有可能。在这个大脑中,核磁共振成像扫描显示有一小部分残留的小脑。此外,尽管有相反的口头说法,但完全没有关于该男子生前运动能力的证据。