• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Pharmaceutical research in molecular oncology.

作者信息

Gibbs J B, Oliff A

机构信息

Department of Cancer Research, Merck Research Laboratories, West Point, Pennsylvania 19486.

出版信息

Cell. 1994 Oct 21;79(2):193-8. doi: 10.1016/0092-8674(94)90189-9.

DOI:10.1016/0092-8674(94)90189-9
PMID:7954788
Abstract
摘要

相似文献

1
Pharmaceutical research in molecular oncology.
Cell. 1994 Oct 21;79(2):193-8. doi: 10.1016/0092-8674(94)90189-9.
2
[Anti-angiogenic reagents].
Tanpakushitsu Kakusan Koso. 2000 Apr;45(6 Suppl):1182-7.
3
Epidermal growth factor-related peptides and their receptors in human malignancies.人类恶性肿瘤中的表皮生长因子相关肽及其受体
Crit Rev Oncol Hematol. 1995 Jul;19(3):183-232. doi: 10.1016/1040-8428(94)00144-i.
4
Receptor protein-tyrosine kinases and their signal transduction pathways.受体蛋白酪氨酸激酶及其信号转导途径。
Annu Rev Cell Biol. 1994;10:251-337. doi: 10.1146/annurev.cb.10.110194.001343.
5
The Sixth George Swanson Christie Memorial Lecture: growth factors and their receptors: new opportunities for cancer treatment.
Pathology. 1994 Oct;26(4):453-63. doi: 10.1080/00313029400169182.
6
[Proto-oncogenes and the control of cell growth].
Duodecim. 1990;106(3):261-77.
7
VEGF receptor signaling in tumor angiogenesis.肿瘤血管生成中的血管内皮生长因子受体信号传导
Oncologist. 2000;5 Suppl 1:3-10. doi: 10.1634/theoncologist.5-suppl_1-3.
8
Vascular atrophy and VEGFR-2 signaling: old theories of pulmonary emphysema meet new data.血管萎缩与血管内皮生长因子受体-2信号传导：肺气肿的旧理论遇上新数据。
J Clin Invest. 2000 Dec;106(11):1309-10. doi: 10.1172/JCI11344.
9
Competition by second messenger systems for receptor interaction and activation: implications for tissue-specific responses and disease therapy.第二信使系统对受体相互作用和激活的竞争：对组织特异性反应和疾病治疗的影响。
Clin Exp Pharmacol Physiol. 1997 Aug;24(8):632-8. doi: 10.1111/j.1440-1681.1997.tb02104.x.
10
Lipocortin V may function as a signaling protein for vascular endothelial growth factor receptor-2/Flk-1.脂皮质素V可能作为血管内皮生长因子受体-2/Flk-1的信号蛋白发挥作用。
Biochem Biophys Res Commun. 1999 May 19;258(3):713-21. doi: 10.1006/bbrc.1999.0678.

引用本文的文献

1
Links between the Prophet Muhammad (PBUH) recommended foods and disease management: A review in the light of modern superfoods.先知穆罕默德（愿主福安之）推荐的食物与疾病管理之间的联系：基于现代超级食物的综述
Int J Health Sci (Qassim). 2018 Mar-Apr;12(2):61-69.
2
Identification of Phosphorylated Cyclin-Dependent Kinase 1 Associated with Colorectal Cancer Survival Using Label-Free Quantitative Analyses.基于无标记定量分析鉴定与结直肠癌生存相关的磷酸化细胞周期蛋白依赖性激酶1
PLoS One. 2016 Jul 6;11(7):e0158844. doi: 10.1371/journal.pone.0158844. eCollection 2016.
3
A "Double-Edged" Scaffold: Antitumor Power within the Antibacterial Quinolone.
一种“双刃剑”支架：抗菌喹诺酮类药物中的抗肿瘤作用
Curr Med Chem. 2016;23(6):520-77. doi: 10.2174/0929867323666151223095839.
4
Nanoparticle delivery of a peptide targeting EGFR signaling.纳米颗粒递呈靶向 EGFR 信号的肽。
J Control Release. 2012 Jan 30;157(2):279-86. doi: 10.1016/j.jconrel.2011.08.014. Epub 2011 Aug 17.
5
An anticancer C-Kit kinase inhibitor is reengineered to make it more active and less cardiotoxic.一种抗癌的C-Kit激酶抑制剂经过重新设计，使其活性更高且心脏毒性更低。
J Clin Invest. 2007 Dec;117(12):4044-54. doi: 10.1172/JCI32373.
6
Kinase packing defects as drug targets.激酶堆积缺陷作为药物靶点。
Drug Discov Today. 2007 Nov;12(21-22):917-23. doi: 10.1016/j.drudis.2007.09.009. Epub 2007 Oct 30.
7
Experimental animal models of pancreatic carcinogenesis and metastasis.胰腺癌发生和转移的实验动物模型
Int J Gastrointest Cancer. 2003;33(1):43-60. doi: 10.1385/IJGC:33:1:43.
8
A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission.丝裂原活化蛋白激酶激酶（MEKs）中一个保守的对接位点介导与丝裂原活化蛋白激酶（MAP激酶）的高亲和力结合，并与一种支架蛋白协同作用以增强信号传递。
J Biol Chem. 2001 Mar 30;276(13):10374-86. doi: 10.1074/jbc.M010271200. Epub 2000 Dec 28.
9
The pursuit of optimal outcomes in cancer therapy in a new age of rationally designed target-based anticancer agents.在合理设计的基于靶点的抗癌药物新时代追求癌症治疗的最佳疗效。
Drugs. 2000;60 Suppl 1:1-14; discussion 41-2. doi: 10.2165/00003495-200060001-00001.
10
Fluorescent oligonucleotide ligation technology for identification of ras oncogene mutations.
Mol Biotechnol. 2000 Mar;14(3):223-33. doi: 10.1385/MB:14:3:223.