McKenna K E, Burrows D
Department of Dermatology, Royal Victoria Hospitals Trust, Belfast, N. Ireland, UK.
Clin Exp Dermatol. 1994 Sep;19(5):419-20. doi: 10.1111/j.1365-2230.1994.tb02699.x.
We report a 19-year-old woman with psoriasis who developed a severe allergic reaction within 1 week of commencement of sulphasalazine; her skin becoming erythrodermic with associated lymphadenopathy, leucopenia and thrombocytopenia. Clinical signs and haematological abnormalities rapidly returned to normal on discontinuation of sulphasalazine. It is important to monitor carefully haematological indices in the early stages of treatment with this drug.
我们报告一名19岁的银屑病女性患者，在开始服用柳氮磺胺吡啶1周内出现严重过敏反应；她的皮肤变成红皮病，并伴有淋巴结病、白细胞减少和血小板减少。停用柳氮磺胺吡啶后，临床症状和血液学异常迅速恢复正常。在使用该药物治疗的早期阶段，仔细监测血液学指标很重要。
