Salmaggi A, Lamperti E, Eoli M, Venegoni E, Bruzzone M G, Riccio G, La Mantia L
Istituto Nazionale Neurologico C. Besta, Milano, Italy.
Clin Exp Rheumatol. 1994 Jul-Aug;12(4):389-94.
We report the clinical, magnetic resonance imaging (MRI) and laboratory findings in 5 patients with clinical spinal cord involvement with an acute or subacute course; in two of the patients the myelitic episode preceded, in one it was concomitant to, and in two it followed the diagnosis of systemic lupus erythematosus (SLE). The marked clinical and MRI heterogeneity detected in our patients suggests that various factors may be implied in the pathogenesis of spinal cord involvement in SLE. The possibility of a future evolution to SLE should be kept in mind in women presenting spinal cord involvement with no other explanation, and should be assessed by means of extensive and repeated clinical and laboratory evaluations.
我们报告了5例临床脊髓受累且病程为急性或亚急性患者的临床、磁共振成像（MRI）及实验室检查结果；其中2例患者在系统性红斑狼疮（SLE）诊断之前出现脊髓炎发作，1例与之同时出现，2例在SLE诊断之后出现。我们的患者中检测到的显著临床和MRI异质性表明，SLE脊髓受累的发病机制可能涉及多种因素。对于无其他病因的脊髓受累女性，应考虑到未来发展为SLE的可能性，并应通过广泛且反复的临床和实验室评估进行评估。
