Introna M, Colotta F, Sozzani S, Dejana E, Mantovani A
Istituto di Richerche Farmacologiche Mario Negri, Milano, Italy.
Clin Exp Rheumatol. 1994 Sep-Oct;12 Suppl 10:S19-23.
Cytokines elicit the expression of distinct sets of functions in endothelium. IL-1 activates endothelium in a prothrombotic-proinflammatory sense. The characteristics and significance of IL-1 inducible genes cloned from endothelial cells is discussed.
细胞因子可诱导内皮细胞表达不同的功能集。白细胞介素-1(IL-1)在促血栓形成-促炎意义上激活内皮细胞。本文讨论了从内皮细胞中克隆的IL-1诱导基因的特征和意义。