Krause W
Endokrinologie. 1976;68(3):267-74.
Male adult, intact rats were treated with 1000 or 2000 mug/kg testosterone propionate (TP), 500 or 1000 mug/kg estradiol benzoate (EB) or ol. arachidis only. 30 min, 24h, 48h and 7 days later they were injected with 5 mug/kg LH-RH or saline solution. 30 min after this FSH, LH and testosterone were determined in plasma by radioimmunoassay. It is shown that pretreatment with 500 mug/kg TP enhances significantly the FSH release after LH-RH even on day 7, while the greater dose of TP does not significantly affect the release of FSH. The LH-RH induced release of LH is also increased by the pretreatment with 500 mug/kg TP, while 2000 mug/kg TP do not alter the reaction to LH-RH. EB in both doses does not influence the LH-RH induced release of FSH and LH.
成年雄性未阉割大鼠分别接受1000或2000微克/千克丙酸睾酮（TP）、500或1000微克/千克苯甲酸雌二醇（EB）处理，或仅给予花生油。30分钟、24小时、48小时和7天后，给它们注射5微克/千克促黄体生成素释放激素（LH-RH）或生理盐水。在此之后30分钟，通过放射免疫测定法测定血浆中的促卵泡生成素（FSH）、促黄体生成素（LH）和睾酮。结果显示，即使在第7天，用500微克/千克TP预处理也能显著增强LH-RH刺激后的FSH释放，而更大剂量的TP对FSH释放无显著影响。用500微克/千克TP预处理也能增加LH-RH诱导的LH释放，而2000微克/千克TP不改变对LH-RH的反应。两种剂量的EB均不影响LH-RH诱导的FSH和LH释放。
