Pan W H, Chen J Y, Chen Y C, Tsai W Y
Division of Epidemiology and Public Health, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan, ROC.
Chin J Physiol. 1994;37(1):49-53.
This study set out to examine the diurnal pattern of electrolyte excretion in urine, and to investigate whether urine collected from after dinner until next morning (half-day evening urine) might to be an alternative to 24-h urine more valid than overnight urine for ranking a person's electrolyte status. In a cross-sectional study of 40 young adults, two consecutive 24-h urine samples were collected, followed one month later by two further consecutive 24-h samples. Mean excretion rates of sodium and chloride steadily increased during the daytime. Electrolyte/creatinine ratios also increased, but all excretion rates decreased after sleep. The potassium excretion rate increased rapidly in the morning but declined steadily after 10 a.m.. Estimates of 24-h electrolyte content calculated from half-day amounts were approximately 80-92% of the actual 24-h urinary electrolyte values. Estimates obtained using overnight urine amounts approximated 60% of the actual 24-h values. Correlation coefficients between actual 24-h urinary electrolytes and estimates based on half-day urine were better than correlates between actual 24-h amounts and estimates obtained using timed overnight urine. These results suggest that half-day evening urine may be a useful alternative to 24-h urine for assessing electrolyte in-take.
本研究旨在检测尿液中电解质排泄的昼夜模式，并调查晚餐后至次日早晨收集的尿液（半日晚尿）是否可能是24小时尿液的一种替代物，用于评估一个人的电解质状况时比过夜尿更有效。在一项针对40名年轻成年人的横断面研究中，连续收集了两份24小时尿液样本，一个月后又连续收集了另外两份24小时样本。钠和氯的平均排泄率在白天稳步增加。电解质/肌酐比值也有所增加，但睡眠后所有排泄率均下降。钾排泄率在早晨迅速上升，但上午10点后稳步下降。根据半日尿量计算的24小时电解质含量估计值约为实际24小时尿液电解质值的80 - 92%。使用过夜尿量获得的估计值约为实际24小时值的60%。实际24小时尿液电解质与基于半日尿的估计值之间的相关系数优于实际24小时量与使用定时过夜尿获得的估计值之间的相关性。这些结果表明，半日晚尿可能是评估电解质摄入量时24小时尿液的一种有用替代物。
