Chen M S, Li J Q, Li G H
Tumour Hospital, Sun Yat-sen University of Medical Science, Guangzhou.
Zhonghua Zhong Liu Za Zhi. 1994 May;16(3):225-7.
One hundred and two patients with histologically diagnosed small hepatocellular carcinoma (< or = 5cm HCC) underwent curative irregular hepatectomy in our hospital from Nov 1972 to Nov 1992. The postoperative survival rates at 1,3,5 and 10 years were 93.9%, 75.3%, 52.8% and 44.6%, respectively. We analysed the clinical factors using a Cox model and found that the clinical staging of HCC, gamma-GT, satellite tumor nodules, tumour capsule and postoperative recurrence have significant effect on the survival rate of patients. We conclude that early diagnosis of sub--clinical HCC, transarterial embolism after hepatectomy to reduce postoperative recurrence, and active treatment with operation and/or TAE after recurrence are effective methods to improve survival of HCC patients.
1972年11月至1992年11月期间，我院对102例经组织学诊断为小肝细胞癌（≤5cm HCC）的患者进行了根治性不规则肝切除术。术后1年、3年、5年和10年的生存率分别为93.9%、75.3%、52.8%和44.6%。我们使用Cox模型分析了临床因素，发现HCC的临床分期、γ-谷氨酰转移酶、卫星肿瘤结节、肿瘤包膜和术后复发对患者的生存率有显著影响。我们得出结论，亚临床HCC的早期诊断、肝切除术后经动脉栓塞以减少术后复发，以及复发后积极进行手术和/或TAE治疗是提高HCC患者生存率的有效方法。
