Rosendahl W, Grunert D, Schöning M
University Children's Hospital, Tübingen, Germany.
Eur J Pediatr. 1994 Aug;153(8):588-93. doi: 10.1007/BF02190666.
Computed duplex sonography was used to examine the renal arteries in 36 hypertensive children and adolescents (ages 4-17 years) with arterial hypertension of either renal or non-renal origin. Time-averaged flow velocities, maximum blood flow velocities as well as absolute renal blood flow and renal blood flow per gram kidney weight were measured. Normal flow velocities and normal to elevated renal blood flow volume was found in patients with acute glomerulonephritis and those with signs of chronic glomerulonephritis onset. Patients having advanced stages of chronic glomerulonephritis, on the other hand, were characterized by lower levels of all parameters. Unilateral renal artery stenosis was diagnosed correctly in four patients, although one intra-renal artery stenosis escaped imaging. Scarred kidneys exhibited low-normal or reduced flow velocities and renal blood flow volumes corresponded roughly to kidney size and preservation of normal kidney structure. Hypertension in some patients with normal kidneys showed a tendency to cause higher renal blood flow without consistent acceleration of blood flow velocities. We conclude that duplex sonography is a suitable primary diagnostic tool in measuring blood flow velocities and absolute renal blood flow volume in hypertensive children, thus facilitating the choice of the next diagnostic step.
采用计算机双功超声检查36例4至17岁患有肾性或非肾性动脉高血压的高血压儿童及青少年的肾动脉。测量了时间平均流速、最大血流速度以及绝对肾血流量和每克肾脏重量的肾血流量。急性肾小球肾炎患者以及有慢性肾小球肾炎发病迹象的患者,其流速正常,肾血流量正常至高值。另一方面,处于慢性肾小球肾炎晚期的患者,其所有参数水平较低。4例患者被正确诊断为单侧肾动脉狭窄,尽管有1例肾内动脉狭窄未被影像学检查发现。瘢痕肾表现为流速略低于正常或降低,肾血流量大致与肾脏大小相符且肾脏结构正常。部分肾脏正常的患者出现高血压时,有导致肾血流量升高的倾向,但血流速度并无持续加快。我们得出结论,双功超声是测量高血压儿童血流速度和绝对肾血流量的合适的初步诊断工具,从而有助于选择下一步诊断措施。