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Western blot as a seroepidemiologic tool for detecting foci of Mediterranean spotted fever (MSF).

作者信息

Raoult D, Arzouni J P, Jambon M C, Beytout J, Ramousse O

机构信息

Unité des Rickettsies, Faculté de Médecine, Marseille, France.

出版信息

Eur J Epidemiol. 1994 Feb;10(1):37-40. doi: 10.1007/BF01717449.

DOI:10.1007/BF01717449
PMID:7957788
Abstract

We conducted a serosurvey on Mediterranean spotted fever (MSF), in a nonendemic area using western blot and microimmunofluorescence. Among 262 tested sera, 53 were positive by micro-immunofluorescence at a titer of 50. When 48 positive sera were western blot tested, 15 did not exhibited any reaction, 17 reacted against the non-specific lipopolysaccharide, and only 16 reacted against the specific protein antigens. Fourteen of the sera with a specific reaction were sampled in a village with a unique submediterranean climate. Western blot may be a more specific tool to determine the real seroprevalence of MSF.

摘要

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Mediterranean spotted fever in Marseille, France: correlation between prevalence of hospitalized patients, seroepidemiology, and prevalence of infected ticks in three different areas.法国马赛的地中海斑疹热:三个不同地区住院患者患病率、血清流行病学与感染蜱虫患病率之间的相关性
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