软骨寡聚基质蛋白（COMP）是肌腱的一种丰富成分。
Cartilage oligomeric matrix protein (COMP) is an abundant component of tendon.
作者信息
DiCesare P, Hauser N, Lehman D, Pasumarti S, Paulsson M
机构信息
Cartilage and Bone Research Center, Hosptial for Joint Diseases Orthopaedic Institute, New York, NY 10003.
出版信息
FEBS Lett. 1994 Nov 7;354(2):237-40. doi: 10.1016/0014-5793(94)01134-6.
An abundant matrix protein was purified under native conditions from adult bovine tendon and identified as cartilage oligomeric matrix protein (COMP) by immunochemical crossreaction, amino acid sequence identity of tryptic peptides derived from both N- and C-terminal regions, and structure revealed by electron microscopy. Immunohistochemistry showed age-dependent differences in distribution of COMP in tendon.
一种丰富的基质蛋白在天然条件下从成年牛肌腱中纯化出来，并通过免疫化学交叉反应、来自N端和C端区域的胰蛋白酶肽段的氨基酸序列一致性以及电子显微镜揭示的结构，被鉴定为软骨寡聚基质蛋白（COMP）。免疫组织化学显示COMP在肌腱中的分布存在年龄依赖性差异。
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