Manners R M, Weller R O
Eye Unit, Southampton General Hospital, UK.
Eye (Lond). 1994;8 ( Pt 3):332-5. doi: 10.1038/eye.1994.68.
A histochemical study of orbicularis oculi was undertaken to test the hypothesis that there is a difference in the percentage and size of muscle fibre types which accounts for the development of involutional ectropion or entropion. Wedge excisions from lower lids of patients undergoing repair of these conditions were frozen-sectioned and stained histochemically to reveal muscle fibre types. Five ectropion and five entropion specimens were obtained, and the percentage of type 1 and type 2 fibres, fibre perimeters and fibre diameters were measured. An abundance of type 2 fibres was found in both ectropion (mean 89.6%) and entropion (mean 82.6%). No significant difference was found with respect to fibre type, perimeter or diameter when ectropion was compared with entropion or when either was compared with normals. Type 2 fibres were larger than type 1 in both ectropion and entropion. We conclude that no significant difference could be identified between orbicularis muscle fibres in ectropion, entropion and normals to account for the development of the eyelid malpositions.
对眼轮匝肌进行了组织化学研究，以检验以下假设：肌纤维类型的百分比和大小存在差异，这是导致退行性睑外翻或睑内翻的原因。对接受这些病症修复手术的患者下眼睑进行楔形切除，制成冰冻切片，并进行组织化学染色以显示肌纤维类型。获取了5个睑外翻和5个睑内翻标本，并测量了1型和2型纤维的百分比、纤维周长和纤维直径。在睑外翻（平均89.6%）和睑内翻（平均82.6%）中均发现大量2型纤维。将睑外翻与睑内翻进行比较，或将两者与正常人进行比较时，在纤维类型、周长或直径方面均未发现显著差异。在睑外翻和睑内翻中，2型纤维均比1型纤维大。我们得出结论，在睑外翻、睑内翻和正常人的眼轮匝肌纤维之间，未发现能解释眼睑错位发展的显著差异。
