Sisler H A, Labay G R, Finlay J R
Ann Ophthalmol. 1976 Mar;8(3):319-22.
A microscopic histopathological study was done on 500 full-eyelid-thickness surgical specimens: 25 with the diagnosis of senile ectropion and 25 with that of senile entropion. Five different staining techniques were used. There appears to be significantly more orbicularis and Riolan's muscle ischemia, atrophy, and collagen fragmentation with ectropion than with entropion. Entropion shows more septal and tarsal atrophy. In both conditions, the skin and conjunctiva show chronic inflammation and scarring as a constant feature. Statistical significance at the 1% level was present for all six characteristics studied. These histopathological changes, if not etiological, are at least concomitant features differentiating senile ectropion from entropion at the microscopic tissue level.
对500份全眼睑厚度手术标本进行了微观组织病理学研究：其中25份诊断为老年性睑外翻，25份诊断为老年性睑内翻。使用了五种不同的染色技术。与睑内翻相比，睑外翻似乎存在明显更多的眼轮匝肌和里奧朗肌缺血、萎缩以及胶原纤维断裂。睑内翻表现出更多的隔膜和睑板萎缩。在这两种情况下，皮肤和结膜均表现出慢性炎症和瘢痕形成，这是一个恒定特征。所研究的所有六个特征在1%水平上均具有统计学意义。这些组织病理学变化，如果不是病因性的，至少是在微观组织水平上区分老年性睑外翻和睑内翻的伴随特征。
