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莫桑比克和瑞典女性中恒河猴抗原分布的产科意义

Obstetric implications of rhesus antigen distribution in Mozambican and Swedish women.

作者信息

Bergström S, Pereira C, Hagström U, Säfwenberg J

机构信息

Department of Obstetrics and Gynecology, Central Hospital, Maputo, Mozambique.

出版信息

Gynecol Obstet Invest. 1994;38(2):82-6. doi: 10.1159/000292454.

Abstract

AB0 and Rhesus phenotypes were analyzed in 199 Mozambican women and the gene frequencies were calculated. The frequencies of the K and Fya antigens were also investigated. The findings were interpreted against the background of the corresponding phenotype distribution of a Swedish population. D- and Du-positive women amounted to 97.0%, which is significantly more than in Sweden (p < 0.001). Among AB0 groups it was found that blood group 0 is significantly more predominant in Mozambican than in Swedish women (p < 0.001). The reverse is true for blood group A (p < 0.001). Blood group B has a similar prevalence in Mozambican and Swedish women. The obstetric implication of the low prevalence of D-negative women is that the Rhesus alloimmunization problem may be of a much smaller magnitude than would be expected.

摘要

对199名莫桑比克女性进行了ABO和恒河猴血型表型分析,并计算了基因频率。还研究了K和Fya抗原的频率。根据瑞典人群相应表型分布的背景对研究结果进行了解释。D阳性和Du阳性女性占97.0%,这一比例显著高于瑞典(p<0.001)。在ABO血型组中,发现莫桑比克女性中O型血的比例显著高于瑞典女性(p<0.001)。A型血的情况则相反(p<0.001)。B型血在莫桑比克和瑞典女性中的患病率相似。D阴性女性患病率较低对产科的影响是,恒河猴血型同种免疫问题可能比预期的要小得多。

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