Hobik E, Ihl R, Kretschmar C
Rheinische Landes- und Hochschulklinik, Heinrich-Heine-Universität Düsseldorf.
Fortschr Neurol Psychiatr. 1994 Sep;62(9):330-6. doi: 10.1055/s-2007-999064.
Cognitive deficits pretending dementia can be caused by thyroid dysfunction. The literature addressing pathophysiology and therapy of thyroid dysfunction is reviewed. A shorter duration and less severe course of thyroid dysfunction seem to indicate a better response to therapy. There are not studies on the latency between therapy and response. It is recommended to measure at least TSH in the differential diagnosis of dementive syndromes. Degenerative dementia can occur in coincidence with thyroid dysfunction. Therapy would improve at least symptoms caused by the thyroid dysfunction.
伪装成痴呆的认知缺陷可能由甲状腺功能障碍引起。本文综述了关于甲状腺功能障碍的病理生理学和治疗的文献。甲状腺功能障碍病程较短且病情较轻似乎表明对治疗反应较好。目前尚无关于治疗与反应之间潜伏期的研究。建议在痴呆综合征的鉴别诊断中至少检测促甲状腺激素(TSH)。退行性痴呆可能与甲状腺功能障碍同时发生。治疗至少会改善由甲状腺功能障碍引起的症状。