Ryan W G, Banks A J
Department of Orthopaedic Surgery, Bolton Royal Infirmary, Lancashire, UK.
Injury. 1994 Sep;25(7):443-5. doi: 10.1016/0020-1383(94)90270-4.
From our experience with the Leeds-Keio artificial ligament at Bolton Hospitals we report the histology from three cases in which the new ligament was demonstrated to have failed in response to trivial injury, after an initially successful anterior cruciate replacement. The histology showed fragmentation of graft material associated with a chronic inflammatory response in the new ligament. A chronic inflammatory response occurs as a result of fragmentation of the Dacron fibres; and once established, inhibits production of the neoligament, thus dooming it to failure.
根据我们在博尔顿医院使用利兹 - 庆应人工韧带的经验，我们报告了三例病例的组织学情况。在最初成功进行前交叉韧带置换后，新韧带因轻微损伤而失效。组织学显示移植材料破碎，并伴有新韧带中的慢性炎症反应。慢性炎症反应是由涤纶纤维破碎引起的；一旦形成，就会抑制新韧带的生成，从而注定其失败。
