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失败的利兹-庆应义塾人工前交叉韧带的组织病理学特征。

Histopathological features of failed prosthetic Leeds-Keio anterior cruciate ligaments.

作者信息

Prescott R J, Ryan W G, Bisset D L

机构信息

Department of Histopathology, Bolton General Hospital, Farnworth.

出版信息

J Clin Pathol. 1994 Apr;47(4):375-6. doi: 10.1136/jcp.47.4.375.

DOI:10.1136/jcp.47.4.375
PMID:8027382
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC501949/
Abstract

Artificial ligaments such as the Leeds-Keio ligament are inserted into knee joints to treat cruciate ligament trauma. Three cases of prosthetic ligament failure are reported, showing foreign body granulomatous inflammation around implanted fibres, together with abundant fibre particles within giant cells. It is suggested that intra-operative fibre fragmentation can produce a sufficient quantity of dendritic particles to elicit a granulomatous reaction, which can ultimately lead to ligament instability and failure.

摘要

诸如利兹-庆应韧带之类的人工韧带被植入膝关节以治疗十字韧带损伤。报告了3例人工韧带失效的病例，显示植入纤维周围有异物肉芽肿性炎症，同时巨细胞内有大量纤维颗粒。提示术中纤维断裂可产生足够数量的树枝状颗粒，引发肉芽肿反应，最终可导致韧带不稳定和失效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7df/501949/2d58eaf62f75/jclinpath00217-0094-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7df/501949/adc5d09f1db1/jclinpath00217-0093-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7df/501949/2d58eaf62f75/jclinpath00217-0094-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7df/501949/adc5d09f1db1/jclinpath00217-0093-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7df/501949/2d58eaf62f75/jclinpath00217-0094-a.jpg

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1
Histopathological features of failed prosthetic Leeds-Keio anterior cruciate ligaments.失败的利兹-庆应义塾人工前交叉韧带的组织病理学特征。
J Clin Pathol. 1994 Apr;47(4):375-6. doi: 10.1136/jcp.47.4.375.
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本文引用的文献

1
Experimental mechanical and histologic evaluation of the Kennedy ligament augmentation device.
Clin Orthop Relat Res. 1985 Jun(196):186-95.
2
Arthroscopy after anterior cruciate reconstruction with the Leeds-Keio ligament.
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Histologic and ultrastructural findings of tissue ingrowth. The Leeds-Keio prosthetic anterior cruciate ligament.
Clin Orthop Relat Res. 1991 Jun(267):115-21.
使用内部支撑增强技术进行同种异体前交叉韧带重建
Arthrosc Tech. 2016 Oct 10;5(5):e1143-e1147. doi: 10.1016/j.eats.2016.06.007. eCollection 2016 Oct.
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Focus on collagen: in vitro systems to study fibrogenesis and antifibrosis state of the art.聚焦胶原蛋白：用于研究纤维化和抗纤维化的体外系统——最新技术水平
Fibrogenesis Tissue Repair. 2009 Dec 15;2:7. doi: 10.1186/1755-1536-2-7.
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Histological and ultrastructural evaluation of Leeds-Keio ligament 20 years after implant: a case report.
Knee Surg Sports Traumatol Arthrosc. 2008 Nov;16(11):1026-9. doi: 10.1007/s00167-008-0608-9. Epub 2008 Sep 10.
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Surface chemistry influences implant biocompatibility.表面化学影响植入物的生物相容性。
Curr Top Med Chem. 2008;8(4):270-80. doi: 10.2174/156802608783790901.
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Ultrastructural study of the extra-articular Leeds-Keio ligament prosthesis.关节外利兹-庆应韧带假体的超微结构研究。
J Clin Pathol. 2005 Jun;58(6):665-6. doi: 10.1136/jcp.2004.024646.
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Histological changes associated with an artificial anterior cruciate ligament.与人工前交叉韧带相关的组织学变化。
J Clin Pathol. 1995 Jun;48(6):556-9. doi: 10.1136/jcp.48.6.556.