O'Mullane D M
Oral Health Services Research Centre, University Dental School, Wilton Cork, Ireland.
Int Dent J. 1994 Jun;44(3 Suppl 1):257-61.
Following the original work of Dean et al. showing the link between fluoride levels in the drinking water and the prevalence of dental fluorosis and dental caries, different strategies aimed at maximising the benefits of fluorides for communities and for individuals have been developed during the last 50 years. The effectiveness of fluoridated salt, fluoride mouthrinses, toothpastes, supplements, gels and varnishes has been extensively investigated in laboratory and human clinical studies. The research effort on the different fluoride strategies has not been confined to measuring effectiveness; other areas which have been extensively investigated include the method of action and metabolism of fluorides. As a result of this research effort it is now possible to adopt a more rational approach to the use of fluorides for caries prevention at community level and for individual patients.
在迪恩等人最初的研究表明饮用水中氟含量与氟斑牙和龋齿患病率之间的联系之后，在过去50年里，人们制定了不同策略，旨在使社区和个人最大限度地受益于氟化物。在实验室和人体临床研究中，已广泛研究了氟化盐、含氟漱口水、牙膏、补充剂、凝胶和 varnishes 的有效性。对不同氟化物策略的研究工作并不局限于衡量有效性；其他已广泛研究的领域包括氟化物的作用方式和代谢。由于这项研究工作，现在有可能在社区层面和针对个体患者采用更合理的方法使用氟化物预防龋齿。
