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阿尔茨海默病:通过皮特斯拉级磁场治疗改善视觉记忆和视觉构建能力

Alzheimer's disease: improvement of visual memory and visuoconstructive performance by treatment with picotesla range magnetic fields.

作者信息

Sandyk R

机构信息

NeuroCommunication Research Laboratories, Danbury, CT 06811.

出版信息

Int J Neurosci. 1994 Jun;76(3-4):185-225. doi: 10.3109/00207459408986003.

DOI:10.3109/00207459408986003
PMID:7960477
Abstract

Impairments in visual memory and visuoconstructive functions commonly occur in patients with Alzheimer's disease (AD). Recently, I reported that external application of electromagnetic fields (EMF) of extremely low intensity (in the picotesla range) and of low frequency (in the range of 5Hz-8Hz) improved visual memory and visuoperceptive functions in patients with Parkinson's disease. Since a subgroup of Parkinsonian patients, specifically those with dementia, have coexisting pathological and clinical features of AD, I investigated in two AD patients the effects of these extremely weak EMF on visual memory and visuoconstructive performance. The Rey-Osterrieth Complex Figure Test as well as sequential drawings from memory of a house, a bicycle, and a man were employed to evaluate the effects of EMF on visual memory and visuoconstructive functions, respectively. In both patients treatment with EMF resulted in a dramatic improvement in visual memory and enhancement of visuoconstructive performance which was associated clinically with improvement in other cognitive functions such as short term memory, calculations, spatial orientation, judgement and reasoning as well as level of energy, social interactions, and mood. The report demonstrates, for the first time, that specific cognitive symptoms of AD are improved by treatment with EMF of a specific intensity and frequency. The rapid improvement in cognitive functions in response to EMF suggests that some of the mental deficits of AD are reversible being caused by a functional (i.e., synaptic transmission) rather than a structural (i.e., neuritic plaques) disruption of neuronal communication in the central nervous system.

摘要

视觉记忆和视觉构建功能受损在阿尔茨海默病(AD)患者中普遍存在。最近,我报告称,对帕金森病患者外部施加极低强度(皮特斯拉范围)和低频(5Hz - 8Hz范围)的电磁场(EMF)可改善其视觉记忆和视觉感知功能。由于一部分帕金森病患者,特别是那些患有痴呆症的患者,同时具有AD的病理和临床特征,我对两名AD患者研究了这些极弱电磁场对视觉记忆和视觉构建能力的影响。分别采用雷 - 奥斯特里茨复杂图形测试以及对房屋、自行车和人物的记忆顺序绘图来评估电磁场对视觉记忆和视觉构建功能的影响。在这两名患者中,电磁场治疗均使视觉记忆得到显著改善,视觉构建能力增强,临床上还伴随着其他认知功能的改善,如短期记忆、计算、空间定向、判断和推理,以及精力水平、社交互动和情绪。该报告首次证明,特定强度和频率的电磁场治疗可改善AD的特定认知症状。对电磁场治疗认知功能的快速改善表明,AD的一些智力缺陷是可逆的,是由中枢神经系统中神经元通讯的功能性(即突触传递)而非结构性(即神经炎性斑块)破坏所致。

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