Merikangas K R, Stevens D E, Angst J
Yale University.
Headache. 1994 Sep;34(8):S17-22. doi: 10.1111/j.1526-4610.1994.hed3408s17.x.
The present study investigated the association between psychopathology and headache in a prospective longitudinal epidemiologic study of a cohort of 19- and 20-year-olds in Zurich, Switzerland. Prevalence rates of psychopathology by headache subtype were examined both cross-sectionally and longitudinally. Psychiatric disorders were evaluated using a direct interview administered by experienced clinicians. Personality was assessed using the Freiburg Personality Inventory and the Symptom Checklist 90. In general, subjects with migraine had more affective and anxiety disorders and exhibited elevated rates of neuroticism and somatization compared to nonmigraine subjects. When examined by headache subtype, migraineurs with aura exhibited greater rates of psychopathology and more personality abnormalities than any of the other headache subtypes or controls. In contrast to clinical wisdom, subjects with tension-type headache did not differ from controls in rates of psychopathology or on any of the personality or symptom factors.
本研究在瑞士苏黎世一项针对19岁和20岁人群队列的前瞻性纵向流行病学研究中,调查了精神病理学与头痛之间的关联。通过横断面和纵向研究,考察了按头痛亚型划分的精神病理学患病率。精神疾病由经验丰富的临床医生通过直接访谈进行评估。使用弗莱堡人格量表和症状自评量表90评估人格。总体而言,与无偏头痛的受试者相比,偏头痛患者有更多的情感和焦虑障碍,且神经质和躯体化发生率更高。按头痛亚型进行检查时,有先兆的偏头痛患者比其他任何头痛亚型或对照组表现出更高的精神病理学发生率和更多的人格异常。与临床认知相反,紧张型头痛患者在精神病理学发生率以及任何人格或症状因素方面与对照组并无差异。