Gerris J, Van Royen E, Mangel-Schots K, Joostens M, de Vits A
Fertility Clinic, Middelheim Hospital, Antwerp, Belgium.
Hum Reprod. 1994 Jul;9(7):1293-6. doi: 10.1093/oxfordjournals.humrep.a138697.
Retrograde ejaculation is an uncommon cause of infertility, which has been treated successfully with different kinds of artificial reproduction technique, e.g. cervical cap artificial insemination by husband, intra-uterine and intraperitoneal insemination, standard in-vitro fertilization, pronuclear stage transfer and gamete intra-Fallopian transfer. All these techniques require a minimal number and motility of spermatozoa obtained after post-masturbation voiding. In some cases, only very few spermatozoa with very poor or no motility are found in the urine voided immediately after masturbation. In such a case, where no more than 14 spermatozoa were recovered over a 3 h search, intracytoplasmic sperm injection of metaphase II oocytes led to the development and replacement of three fair embryos, resulting in an ongoing twin pregnancy. This technique opens up perspectives for the treatment of men with complete retrograde ejaculation and quasi-azoospermic post-voiding specimens.
逆行射精是一种罕见的不育原因，已通过不同种类的人工生殖技术成功治疗，例如丈夫宫颈帽人工授精、子宫内和腹腔内授精、标准体外受精、原核期移植和配子输卵管内移植。所有这些技术都要求手淫后排尿所获得的精子数量和活力达到最低标准。在某些情况下，手淫后立即排出的尿液中仅发现极少量活力很差或无活力的精子。在这种情况下，若在3小时的搜寻中回收的精子不超过14条，对处于减数分裂中期II的卵母细胞进行胞浆内精子注射可促使三个优质胚胎发育并移植，从而实现持续的双胎妊娠。该技术为治疗完全逆行射精且手淫后排尿标本几乎无精子的男性开辟了前景。
