Okada Hiroshi, Goda Kazumasa, Koshida Mitsunobu, Kamidono Sadao
Division of Urology, Department of Organ Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
J Reprod Med. 2004 May;49(5):389-91.
Owing to the prevalence of diabetes mellitus, spinal injuries and aggressive surgical treatment of cancer, the number of younger patients with retrograde ejaculation is increasing. Since medical treatment to restore antegrade ejaculation often fails, several options for accomplishing insemination by these patients, including the use of sperm-rich urine obtained after masturbation and in vitro fertilization with sperm retrieved from the seminal tract, have been reported. We used the least invasive and most inexpensive procedure in a patient/couple with this condition.
A 23-year-old man suffered from retrograde ejaculation after a spinal injury. He could achieve erection and engage in sexual intercourse but seldom had an orgasm or the sensation of ejaculation. We obtained spermatozoa from urine produced after masturbation at home and froze them. We used these frozen-thawed spermatozoa for intrauterine insemination, leading to the term birth of a healthy infant.
In selected patient/couples, frozen spermatozoa obtained from postmasturbation urine can be used successfully for intrauterine insemination. This minimally invasive and most inexpensive procedure should be tried before planning in vitro fertilization.
由于糖尿病、脊髓损伤的普遍存在以及癌症的积极手术治疗，逆行射精的年轻患者数量正在增加。由于恢复顺行射精的药物治疗往往失败，已有报道称这些患者实现授精的几种选择，包括使用手淫后获得的富含精子的尿液以及从生殖道获取精子进行体外受精。我们在患有这种情况的患者/夫妇中采用了侵入性最小且最廉价的程序。
一名23岁男性在脊髓损伤后出现逆行射精。他能够勃起并进行性交，但很少有性高潮或射精感觉。我们从他在家手淫后产生的尿液中获取精子并将其冷冻。我们使用这些冻融后的精子进行宫内授精，最终产下一名健康婴儿。
在选定的患者/夫妇中，从手淫后尿液中获得的冷冻精子可成功用于宫内授精。在计划体外受精之前，应尝试这种微创且最廉价的程序。
