Metabolic and genetic characterization of prediabetic states. Sequence of events leading to non-insulin-dependent diabetes mellitus.
作者信息
Beck-Nielsen H, Groop L C
机构信息
Medical Endocrinological Department M, Odense University Hospital.
出版信息
J Clin Invest. 1994 Nov;94(5):1714-21. doi: 10.1172/JCI117518.
Abstract
摘要
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Metabolic and genetic characterization of prediabetic states. Sequence of events leading to non-insulin-dependent diabetes mellitus.糖尿病前期状态的代谢和遗传特征。导致非胰岛素依赖型糖尿病的事件序列。
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本文引用的文献
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Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"?糖尿病：一种因“进步”而变得有害的“节俭”基因型？
Am J Hum Genet. 1962 Dec;14(4):353-62.
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Glycogen synthase and phosphofructokinase protein and mRNA levels in skeletal muscle from insulin-resistant patients with non-insulin-dependent diabetes mellitus.非胰岛素依赖型糖尿病胰岛素抵抗患者骨骼肌中糖原合酶和磷酸果糖激酶的蛋白质及mRNA水平
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Assignment of the gene encoding glycogen synthase (GYS) to human chromosome 19, band q13.3.
Genomics. 1993 Feb;15(2):460-1. doi: 10.1006/geno.1993.1092.
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Association between polymorphism of the glycogen synthase gene and non-insulin-dependent diabetes mellitus.糖原合酶基因多态性与非胰岛素依赖型糖尿病之间的关联。
N Engl J Med. 1993 Jan 7;328(1):10-4. doi: 10.1056/NEJM199301073280102.
5
Abnormal activation of glycogen synthesis in fibroblasts from NIDDM subjects. Evidence for an abnormality specific to glucose metabolism.非胰岛素依赖型糖尿病（NIDDM）患者成纤维细胞中糖原合成的异常激活。葡萄糖代谢特异性异常的证据。
Diabetes. 1993 Apr;42(4):583-9. doi: 10.2337/diab.42.4.583.
6
Human hexokinase II: localization of the polymorphic gene to chromosome 2.人类己糖激酶II：多态性基因在2号染色体上的定位。
Diabetologia. 1993 Dec;36(12):1299-302. doi: 10.1007/BF00400809.
7
Rad: a member of the Ras family overexpressed in muscle of type II diabetic humans.Rad：Ras家族的一个成员，在II型糖尿病患者的肌肉中过度表达。
Science. 1993 Nov 26;262(5138):1441-4. doi: 10.1126/science.8248782.
8
Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.非胰岛素依赖型糖尿病中胰岛素受体底物-1的氨基酸多态性
Lancet. 1993 Oct 2;342(8875):828-32. doi: 10.1016/0140-6736(93)92694-o.
9
Effect of insulin on GLUT-4 mRNA and protein concentrations in skeletal muscle of patients with NIDDM and their first-degree relatives.胰岛素对非胰岛素依赖型糖尿病患者及其一级亲属骨骼肌中葡萄糖转运蛋白4（GLUT-4）mRNA和蛋白质浓度的影响。
Diabetologia. 1994 Apr;37(4):401-7. doi: 10.1007/BF00408478.
10
Glycogen synthase: a putative locus for diet-induced hyperglycemia.糖原合酶：饮食诱导的高血糖的一个假定位点。
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