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一名原发性血小板增多症且有复发性流产病史的患者在接受羟基脲治疗后怀孕。

Pregnancy after treatment with hydroxyurea in a patient with primary thrombocythaemia and a history of recurrent abortion.

作者信息

Cinkotai K I, Wood P, Donnai P, Kendra J

机构信息

Department of Haematology, Manchester Royal Infirmary.

出版信息

J Clin Pathol. 1994 Aug;47(8):769-70. doi: 10.1136/jcp.47.8.769.

Abstract

A 28 year old patient with primary thrombocythaemia, who had had two stillbirths in the third trimester, is reported. She was successfully treated with hydroxyurea and delivered a healthy 6lb boy by elective caesarean section. The ease with which this treatment can be given, its high level of tolerance among patients, and its low cost are likely to increase its use as a safe and effective treatment in pregnant patients with primary thrombocythaemia.

摘要

报道了一名28岁原发性血小板增多症患者,她在妊娠晚期有两次死产经历。她接受羟基脲治疗成功,并通过选择性剖宫产分娩了一个健康的6磅重男婴。这种治疗给药简便、患者耐受性高且成本低,可能会增加其作为原发性血小板增多症妊娠患者安全有效治疗方法的应用。

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本文引用的文献

1
Hydroxyurea treatment for chronic myeloid leukaemia during pregnancy.
Br J Haematol. 1993 Sep;85(1):203-4. doi: 10.1111/j.1365-2141.1993.tb08672.x.
2
Busulfan in early pregnancy.孕早期使用白消安。
Obstet Gynecol. 1966 May;27(5):738-40.
4
Primary thrombocythemia in pregnancy: a report of two cases.妊娠期原发性血小板增多症:两例报告
Am J Obstet Gynecol. 1988 Jul;159(1):127-8. doi: 10.1016/0002-9378(88)90507-8.
5
Primary thrombocythaemia in pregnancy.妊娠期原发性血小板增多症
Br J Haematol. 1991 Mar;77(3):371-4. doi: 10.1111/j.1365-2141.1991.tb08586.x.
7
Hydroxyurea and pregnancy.
Am J Obstet Gynecol. 1992 Jun;166(6 Pt 1):1868. doi: 10.1016/0002-9378(92)91590-7.
8
Pregnancy during myelosuppressive treatment for chronic myelogenous leukemia.
Br J Haematol. 1992 Dec;82(4):783-4. doi: 10.1111/j.1365-2141.1992.tb06968.x.

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