Kirchmann T T, Smoller B R, McGuire J
Department of Dermatology, Stanford University Medical Center, Palo Alto, CA 94304.
J Am Acad Dermatol. 1994 Nov;31(5 Pt 2):861-6. doi: 10.1016/s0190-9622(94)70247-0.
Angiosarcoma is a rare and highly malignant neoplasm. Cutaneous angiosarcoma not associated with postmastectomy lymphedema is rare. There are only eight reported cases of development of cutaneous angiosarcoma in a lymphedematous extremity in a patient with preexisting malignancy other than breast cancer. This is the first reported case of development of cutaneous angiosarcoma in a lymphedematous extremity in a Hodgkin's disease survivor. A review of cutaneous angiosarcoma associated with lymphedema and a discussion of the pathogenesis of angiosarcoma are included.
血管肉瘤是一种罕见的高度恶性肿瘤。与乳房切除术后淋巴水肿无关的皮肤血管肉瘤很罕见。仅有8例报告称，除乳腺癌外，已有恶性肿瘤的患者在淋巴水肿的肢体上发生皮肤血管肉瘤。这是首例关于霍奇金淋巴瘤幸存者在淋巴水肿肢体上发生皮肤血管肉瘤的报告。本文包括对与淋巴水肿相关的皮肤血管肉瘤的综述以及对血管肉瘤发病机制的讨论。
