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静脉注射免疫球蛋白治疗对其他治疗无反应的慢性炎症性脱髓鞘性多发性神经病患者。

Intravenous immunoglobulin treatment in patients with chronic inflammatory demyelinating neuropathy not responsive to other treatments.

作者信息

Nemni R, Amadio S, Fazio R, Galardi G, Previtali S, Comi G

机构信息

Department of Neurology, University of Milan, Scientific Institute S Raffaele, Italy.

出版信息

J Neurol Neurosurg Psychiatry. 1994 Nov;57 Suppl(Suppl):43-5. doi: 10.1136/jnnp.57.suppl.43.

Abstract

Nine patients with chronic inflammatory demyelinating poliradiculoneuropathy (CIDP) were treated with intravenous immunoglobulin. All patients had been previously treated with prednisone and/or plasma exchange without effect. Objective improvement in clinical condition occurred in six patients. One patient became refractory after two treatment courses, two patients had no response. The results indicate that intravenous immunoglobulin has beneficial effects in a high percentage of patients with CIDP who are unresponsive to other treatments.

摘要

9例慢性炎症性脱髓鞘性多发性神经根神经病(CIDP)患者接受了静脉注射免疫球蛋白治疗。所有患者此前均接受过泼尼松和/或血浆置换治疗,但均无效果。6例患者的临床状况有客观改善。1例患者在两个疗程后变得难治,2例患者无反应。结果表明,静脉注射免疫球蛋白对大部分对其他治疗无反应的CIDP患者有有益作用。

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