Wotherspoon A C, Hardman-Lea S, Isaacson P G
Department of Histopathology, University College London Medical School, U.K.
J Pathol. 1994 Sep;174(1):33-7. doi: 10.1002/path.1711740106.
The recent description of conjunctival lymphomas with features of lymphomas that arise in mucosa-associated lymphoid tissue (MALT) infers the presence of MALT in the human conjunctiva. Some authors suggest that organized MALT is found in the normal human conjunctiva, but others disagree. In order to resolve this problem, we have examined the conjunctival fornix from unselected autopsies with no prior history of conjunctival or ocular disease for the presence of organized MALT. In only 31 per cent of cases was organized lymphoid tissue found with the morphological and immunophenotypic features of MALT. This finding suggests that MALT is not found in the normal human conjunctiva but is acquired during life in a proportion of apparently asymptomatic individuals.
近期对具有黏膜相关淋巴组织（MALT）淋巴瘤特征的结膜淋巴瘤的描述提示人结膜中存在MALT。一些作者认为在正常人结膜中可发现有组织的MALT，但其他作者则持不同意见。为了解决这一问题，我们对未经挑选的、既往无结膜或眼部疾病史的尸检结膜穹窿进行检查，以确定是否存在有组织的MALT。仅在31%的病例中发现了具有MALT形态学和免疫表型特征的有组织淋巴组织。这一发现表明，正常人结膜中不存在MALT，而是在一部分明显无症状个体的生命过程中获得的。
