Hanukoglu A, Bistritzer T, Rakover Y, Mandelberg A
Departments of Pediatrics and Pulmonary Diseases, E. Wolfson Medical Center, Holon, Israel.
J Pediatr. 1994 Nov;125(5 Pt 1):752-5. doi: 10.1016/s0022-3476(94)70071-0.
Four patients with severe pseudohypoaldosteronism caused by multiple end-organ resistance to aldosterone had frequently recurring lower respiratory tract infections and persistently elevated sweat and saliva electrolyte values. The increased saliva electrolyte values in these patients probably affect normal mucociliary function in the respiratory tract and facilitate the occurrence of frequent lower respiratory tract involvement. Patients with pseudohypoaldosteronism may require treatment similar to that for cystic fibrosis to prevent long-term respiratory complications.
四名因多个终末器官对醛固酮产生抵抗而导致严重假性醛固酮减少症的患者，下呼吸道感染频繁复发，汗液和唾液电解质值持续升高。这些患者唾液电解质值升高可能会影响呼吸道正常的黏液纤毛功能，并促使下呼吸道频繁受累。假性醛固酮减少症患者可能需要与囊性纤维化患者类似的治疗，以预防长期的呼吸道并发症。
