Stockman A, Varigos G A, Muirden K D
Med J Aust. 1976 Nov 27;2(22):819-21. doi: 10.5694/j.1326-5377.1976.tb115394.x.
This paper reports a double-blind crossover trial comparing mefenamic acid (1500 mg/day) with ibuprofen (1200 mg/day) in the treatment of patients with rheumatoid arthritis receiving maintenance salicylate therapy. Both drugs were used in three divided doses. Mefenamic acid compared favourably with ibuprofen. In the adopted dose regimes the side effects from both drugs were mild and almost exclusively gastrointestinal.
本文报道了一项双盲交叉试验，该试验比较了甲芬那酸（1500毫克/天）和布洛芬（1200毫克/天）对接受水杨酸维持治疗的类风湿性关节炎患者的治疗效果。两种药物均分三次服用。甲芬那酸的治疗效果优于布洛芬。在采用的剂量方案中，两种药物的副作用都很轻微，且几乎都仅为胃肠道副作用。
