酮洛芬与布洛芬治疗类风湿性关节炎的双盲、多中心平行试验。
Double-blind, multi-centre parallel trial of ketoprofen and ibuprofen in the treatment of rheumatoid arthritis.
作者信息
Calin A, Bennett R M, Sukhupunyaraksa S, Goldman A L, Montoya H E, O'Brien W M, Giuliano V J, Schmid F R, Willkens R F, Sakofsky H Y
出版信息
J Rheumatol. 1977 Summer;4(2):153-7.
PMID:328880
Abstract
A double-blind parallel multi-centre study of 102 patients with rheumatoid arthritis (RA) was performed, comparing ibuprofen (1200-2400 mg daily) and ketoprofen (150-300 mg daily) a new non-steroidal, anti-inflammatory agent, over a three month period. Ketoprofen was well tolerated and shown to have comparable efficacy with ibuprofen. Longterm efficacy and tolerance studies are indicated.
摘要
对102例类风湿性关节炎（RA）患者进行了一项双盲平行多中心研究，在三个月的时间里比较布洛芬（每日1200 - 2400毫克）和酮洛芬（每日150 - 300毫克，一种新型非甾体抗炎药）。酮洛芬耐受性良好，且显示出与布洛芬相当的疗效。有必要进行长期疗效和耐受性研究。
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