Frank W, Stuhldreher D, Saffrin R, Shott S, Guinan P
Department of Urology, University of Illinois, Chicago.
J Urol. 1994 Dec;152(6 Pt 1):1998-9. doi: 10.1016/s0022-5347(17)32289-9.
Data from 104 patients with stage IV renal cell carcinoma were evaluated to investigate relationships between survival and gender, race, age, tumor size, lung versus bone metastasis, number of metastatic sites and nephrectomy. No statistically significant differences in survival were found between gender or racial groups, nor was there a statistically significant relationship between survival and patient age. Survival tended to decrease as tumor size increased. Survival was worse for patients with multiple metastatic sites compared to those with only 1 metastatic site, and for patients with bone and lung metastases compared to those with lung but no bone metastases and bone but no lung metastases. Although nephrectomy patients appeared to have somewhat better survival rates than those without nephrectomy, this difference was apparently due to better prognostic factors for nephrectomy patients.
对104例IV期肾细胞癌患者的数据进行评估，以研究生存与性别、种族、年龄、肿瘤大小、肺转移与骨转移、转移部位数量及肾切除术之间的关系。性别或种族组之间在生存方面未发现有统计学意义的差异，生存与患者年龄之间也没有统计学意义的关系。生存倾向于随着肿瘤大小的增加而降低。与仅有1个转移部位的患者相比，有多个转移部位的患者生存情况更差；与有肺转移但无骨转移以及有骨转移但无肺转移的患者相比，有骨和肺转移的患者生存情况更差。尽管接受肾切除术的患者似乎比未接受肾切除术的患者生存率略高，但这种差异显然是由于接受肾切除术的患者具有更好的预后因素。
