Orihuela E, Motamedi M, Cammack T, Torres J H, Pow-Sang M, Lahaye M, Cowan D F, Warren M M
Department of Surgery, University of Texas Medical Branch, Galveston 77555.
J Urol. 1995 Jan;153(1):196-200. doi: 10.1097/00005392-199501000-00076.
We compared the thermocoagulation effects of low power, slow heating (15 W x 180 seconds) versus high power, rapid heating (50 W x 60 seconds) laser regimens in the canine prostate. The study was performed in 20 mongrel canines. On each prostate, the low power regimen was delivered at the 2 and 4 o'clock positions, and the high power at the 8 and 10 o'clock positions. The laser power was measured at the fiber tip. Seven dogs (acute group) were sacrificed 1 hour after the procedure. The other 13 dogs (chronic group) were sacrificed at different time intervals from 3 days to 9 weeks after the procedure. The average depth of coagulation was significantly greater in lesions treated at low power (acute: 10.7 mm., chronic: 13.3 mm.) than in those treated at high power (acute: 8.5 mm., chronic: 11.6 mm.). Another potential benefit of the low power regimen observed in the study was preservation of the integrity and efficiency of the laser probe.
我们比较了低功率、缓慢加热（15瓦×180秒）与高功率、快速加热（50瓦×60秒）激光方案对犬前列腺的热凝效果。该研究在20只杂种犬身上进行。在每个前列腺上，低功率方案在2点和4点位置实施，高功率方案在8点和10点位置实施。在光纤尖端测量激光功率。7只犬（急性组）在手术后1小时处死。另外13只犬（慢性组）在手术后3天至9周的不同时间间隔处死。低功率治疗的病变平均凝固深度（急性：10.7毫米，慢性：13.3毫米）显著大于高功率治疗的病变（急性：8.5毫米，慢性：11.6毫米）。该研究中观察到的低功率方案的另一个潜在益处是保留了激光探头的完整性和效率。
