Ishikawa M, Suzuki S, Akutu Y, Toyota T, Nose M, Sakai H, Mori K
Third Department of Internal Medicine, Tohoku University School of Medicine.
Rinsho Ketsueki. 1994 Sep;35(9):886-91.
We describe a 39 years-old male hemophilia A patient with acquired immunodeficiency syndrome (AIDS) developing to disseminated intravascular coagulation (DIC) due to gastric carcinoma. He had been diagnosed as human immunodeficiency virus (HIV) sero-positive in 1990. Since then, he has been treated by the oral administration of zidovudine (AZT), dideoxyinosine (ddI) and intravenous administration of glycyrrhizin. In September 1990, he suddenly complained abdominal pain with bloody stool. His condition deteriorated in spite of our intensive treatment for DIC. He died of multiple organ failure (MOF) due to DIC. The autopsy findings showed gastric carcinoma, defined of signet ring cell carcinoma histopathologically. But neither opportunistic infection nor other cause of DIC were observed.
我们描述了一名39岁的甲型血友病男性患者，他患有获得性免疫缺陷综合征（AIDS），因胃癌发展为弥散性血管内凝血（DIC）。他于1990年被诊断为人免疫缺陷病毒（HIV）血清学阳性。从那时起，他一直通过口服齐多夫定（AZT）、双脱氧肌苷（ddI）以及静脉注射甘草酸进行治疗。1990年9月，他突然出现腹痛并伴有便血。尽管我们对DIC进行了强化治疗，他的病情仍恶化。他死于因DIC导致的多器官功能衰竭（MOF）。尸检结果显示为胃癌，组织病理学上为印戒细胞癌。但未观察到机会性感染或其他DIC病因。
