Uchida T, Midorikawa J, Takeda H, Shichishima T, Higuchi T, Yui T, Kimura H, Matsuda S, Kariyone S
First Department of Internal Medicine, Fukushima Medical College.
Jpn J Clin Oncol. 1989 Mar;19(1):75-8.
A case of signet cell carcinoma associated with AIDS is presented. A 50-year old Japanese man with hemophilia A was suffering from human immunodeficiency virus (HIV) infection, the result of multiple injections of clotting factor concentrates. A diagnosis of signet cell carcinoma of the stomach was reached upon endoscopic and histological examinations. Opportunistic infections of esophageal candidiasis and candida septicemia occurred. The patient died of repeated gastrointestinal bleeding and cachexia. Although there is a possibility of the patient having a coincidential carcinoma along with AIDS, the HIV infection, perhaps, had a role in causing signet cell cercinoma.
本文报告一例与艾滋病相关的印戒细胞癌病例。一名50岁的日本男性，患有甲型血友病，因多次注射凝血因子浓缩物而感染人类免疫缺陷病毒（HIV）。经内镜及组织学检查确诊为胃印戒细胞癌。患者发生了食管念珠菌病和念珠菌败血症等机会性感染。患者死于反复的胃肠道出血和恶病质。尽管患者有可能同时患有与艾滋病无关的癌症，但HIV感染或许在导致印戒细胞癌方面起到了一定作用。
