[Septo-clean*新型消毒剂和防腐剂]
[Septo-clean* new disinfecting agent and antiseptic].
作者信息
Muszyński Z, Długaszewska J
机构信息
Katedra i Zakład Bakteriologii Farmaceutycznej AM w Poznaniu.
出版信息
Med Dosw Mikrobiol. 1994;46(1-2):91-4.
The study was aimed at evaluation of usefulness of Septo-Clean, which contain in 100 cm3 of distilled water 1 g of didecyl-dimethylammonium chloride and 70 cm3 of isopropyl alcohol. This preparation is prepared for quick disinfection of surfaces and antiseptic action on hand skin. Investigations were carried on test strains of S. aureus, E. coli, P. aeruginosa and C. albicans. It was demonstrated that MIC of Septo-Clean amount to 0.04% for S. aureus to 0.88% for P. aeruginosa. MBC 5 min values were respectively 0.19 and 1.05%. It was found that this preparation effectively lowers natural contamination with bacteria of hospital usable surfaces by 98%, exhibiting effectiveness similar to preparations containing 2.5% of chlorhexidine in 70% ethanol or isopropanol.
该研究旨在评估“Septo - Clean”的效用，其在100立方厘米蒸馏水中含有1克二癸基二甲基氯化铵和70立方厘米异丙醇。这种制剂用于快速对表面进行消毒以及对手部皮肤起到抗菌作用。研究针对金黄色葡萄球菌、大肠杆菌、铜绿假单胞菌和白色念珠菌的测试菌株展开。结果表明，“Septo - Clean”对金黄色葡萄球菌的最低抑菌浓度为0.04%，对铜绿假单胞菌为0.88%。5分钟的最低杀菌浓度值分别为0.19%和1.05%。研究发现，这种制剂能有效将医院常用表面的细菌自然污染降低98%，其效果与含有2.5%氯己定的70%乙醇或异丙醇制剂相似。
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