亚抑菌浓度洛美沙星对细菌黏附的影响。
Effect of subinhibitory concentrations of lomefloxacin on bacterial adherence.
作者信息
Ravizzola G, Longo M, Pollara P, De Francesco M, Pizzi R
机构信息
Istituto di Microbiologia, Spedali Civili, Brescia, Italy.
出版信息
New Microbiol. 1994 Jul;17(3):211-6.
We studied the effect of subinhibitory concentrations of lomefloxacin on bacterial adherence, assessing the presence of fimbriae in E. coli and the adherence to uroepithelial cells of Staphylococcus saprophyticus. The degree of inhibition of fimbriae in E. coli in the log-phase is directly proportional to subminimal inhibiting concentrations (sub-MIC). On the contrary, there is no effect when the bacteria are in a stationary phase. In the case of Staphylococcus saprophyticus the adherence to epithelial cells was observed at concentrations of 1/2 and 1/4 the MIC.
我们研究了亚抑菌浓度的洛美沙星对细菌黏附的影响，评估了大肠杆菌中菌毛的存在情况以及腐生葡萄球菌对尿道上皮细胞的黏附情况。对数期大肠杆菌菌毛的抑制程度与亚最小抑菌浓度（亚MIC）成正比。相反，当细菌处于稳定期时则没有影响。对于腐生葡萄球菌，在1/2和1/4 MIC浓度下观察到其对上皮细胞的黏附。
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