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巴西东北部健康人群及肾移植患者中的人类T细胞白血病病毒1型(HTLV-1)抗体

Human T cell leukemia virus type 1 (HTLV-1) antibodies in healthy populations and renal transplanted patients in the north-east of Brazil.

作者信息

Linhares M I, Eizuru Y, de Andrade G P, Fonseca I B, Carvalho Júnior L B, Moreira I T, Minamishima Y

机构信息

Laboratorio de Imunopatologia Keizo Asami, Setor de Virologia, Universidade Federal de Pernambuco, Recife, Brazil.

出版信息

Microbiol Immunol. 1994;38(6):475-8. doi: 10.1111/j.1348-0421.1994.tb01811.x.

DOI:10.1111/j.1348-0421.1994.tb01811.x
PMID:7968679
Abstract

The seroprevalence of human T cell leukemia virus type 1 (HTLV-1) infection was investigated in Brazilians (570): native inhabitants (298) and descendants from Japanese (272) living in Recife and its neighborhoods--North-east of Brazil. Furthermore, polytransfused renal transplanted patients (54) were also examined for the serological status to this virus. The seropositivity to HTLV-1, screened by enzyme-linked immunosorbent assay (ELISA), was low: 1.34% for the local population and 0.73% for the descendants from Japanese. However, the seropositivity for the renal transplanted patients was found to be 11.1%. This higher value suggests that this retrovirus infection seems to be of importance in this clinical condition.

摘要

在巴西人(570名)中调查了人类T细胞白血病病毒1型(HTLV-1)感染的血清阳性率,这些巴西人包括居住在巴西东北部累西腓及其周边地区的当地居民(298名)和日本后裔(272名)。此外,还对接受多次输血的肾移植患者(54名)进行了该病毒血清学状态的检查。通过酶联免疫吸附测定(ELISA)筛查的HTLV-1血清阳性率较低:当地人群为1.34%,日本后裔为0.73%。然而,肾移植患者的血清阳性率为11.1%。这一较高的值表明,这种逆转录病毒感染在这种临床情况下似乎具有重要意义。

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