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巴西亚马逊地区人群中人类T细胞白血病病毒I型(HTLV-I)抗体的流行情况(初步报告)

Prevalence of human T cell leukemia virus-I (HTLV-I) antibody among populations living in the Amazon region of Brazil (preliminary report).

作者信息

Nakauchi C M, Linhares A C, Maruyama K, Kanzaki L I, Macedo J E, Azevedo V N, Casseb J S

机构信息

Instituto Evandro Chagas, Fundação Serviços de Saúde Pública, Belém, PA, Brasil.

出版信息

Mem Inst Oswaldo Cruz. 1990 Jan-Mar;85(1):29-33. doi: 10.1590/s0074-02761990000100004.

DOI:10.1590/s0074-02761990000100004
PMID:2215230
Abstract

Forty-three (31.4%) out of 137 serum samples obtained from two Indian communities living in the Amazon region were found to be positive for HTLV-I antibody, as tested by enzyme-linked immunosorbent assay (ELISA). Eighty-two sera were collected from Mekranoiti Indians, yielding 39% of positivity, whereas 11 (20.0%) of the 55 Tiriyo serum samples had antibody to HTLV-I. In addition, positive results occurred in 10 (23.2%) out of 43 sera obtained from patients living in the Belem area, who were suffering from cancer affecting different organs. Five (16.7%) out of 30 ELISA positive specimens were also shown to be positive by either Western blot analysis (WB) or indirect immunogold electron microscopy (IIG-EM).

摘要

通过酶联免疫吸附测定(ELISA)检测发现,从生活在亚马逊地区的两个印度社区采集的137份血清样本中,有43份(31.4%)HTLV-I抗体呈阳性。从梅克拉诺伊蒂印第安人那里采集了82份血清,阳性率为39%,而55份蒂里尤血清样本中有11份(20.0%)含有抗HTLV-I抗体。此外,从贝伦地区患有不同器官癌症的患者那里采集的43份血清中,有10份(23.2%)检测结果呈阳性。30份ELISA阳性标本中有5份(16.7%)通过蛋白质印迹分析(WB)或间接免疫金电子显微镜检查(IIG-EM)也显示为阳性。

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