酮洛芬治疗类风湿性关节炎
Ketoprofen in the treatment of rheumatoid arthritis.
作者信息
Kennedy A C
出版信息
Rheumatol Rehabil. 1976;Suppl:34-6. doi: 10.1093/rheumatology/15.5.34.
PMID:796938
Abstract
A double-blind cross-over trial of ketoprofen (200 mg daily) compared with placebo and aspirin (4 g daily) was carried out in 24 patients with rheumatoid arthritis. Ketoprofen was shown to be significantly more effective than placebo in terms of pain relief, degree and duration of morning stiffness, articular index and patients' assessment of improvement. No significant differences were noted between ketoprofen and aspirin, although side-effects were less with ketoprofen.
摘要
对24例类风湿性关节炎患者进行了一项双盲交叉试验，比较了酮洛芬（每日200毫克）与安慰剂及阿司匹林（每日4克）的疗效。结果显示，在缓解疼痛、晨僵程度和持续时间、关节指数以及患者对病情改善的评估方面，酮洛芬比安慰剂显著更有效。虽然酮洛芬的副作用较少，但酮洛芬与阿司匹林之间未观察到显著差异。
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