一项关于酮洛芬（直肠给药）治疗髋部和膝部关节炎的对照试验。
A controlled trial of ketoprofen (administered rectally) in arthritis of the hip and knee.
作者信息
Rondier J, Cayla J, Menkes C J
出版信息
Rheumatol Rehabil. 1976;Suppl:71-4. doi: 10.1093/rheumatology/15.5.71.
PMID:796950
Abstract
A double-blind therapeutic trial carried out by the sequential method has demonstrated clearly a significant difference in efficacy between ketoprofen (given rectally at a dosage of 200 mg daily) and a placebo in a group of patients suffering from osteoarthritis of the hip or knee. The interest in this type of study lies in the fact that it will often given the answer to a simple question using a relatively small number of patients.
摘要
一项采用序贯法进行的双盲治疗试验清楚地表明，在一组髋部或膝部骨关节炎患者中，酮洛芬（每日直肠给药200毫克）与安慰剂在疗效上存在显著差异。这类研究的意义在于，它常常能用相对较少的患者数量回答一个简单的问题。
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