David-Chaussé J, Dehais J, Bullier R
Rheumatol Rehabil. 1976;Suppl:57-8. doi: 10.1093/rheumatology/15.5.57.
The results of a clinical study of ketoprofen suppositories suggest that the drug is effective when given in this way. It is suggested that, in the treatment of inflammatory rheumatic disorders, advantage should be taken of the longer duration of action of ketoprofen suppositories to prescribe their administration early in the morning and before retiring. Local intolerance occurred in only 4 of 52 patients.
酮洛芬栓剂的一项临床研究结果表明,以这种方式给药时该药物是有效的。建议在治疗炎性风湿性疾病时,应利用酮洛芬栓剂作用持续时间较长的特点,在清晨和睡前给药。52名患者中仅有4名出现局部不耐受。