Kandil M R, Tohamy S A, Fattah M A, Ahmed H N, Farwiez H M
Neurology Department, Faculty of Medicine, Assiut University, Egypt.
Neuroepidemiology. 1994;13(5):202-10. doi: 10.1159/000110380.
Involuntary movements originate from different parts of the nervous system. The character of movements depends upon the site of the lesion and the type of pathological change. The presence of more than one type of involuntary movement in a patient can cause confusion and difficulty in the proper classification of movement disorders, which then leads to problems in the differential diagnosis and appropriate treatment. This work was planned to estimate the prevalence and to study the aetiological factors of chorea, dystonia, athetosis and hemiballismus in Assiut, a representative community of Upper Egypt. This study was carried out on 7,000 families (42,000 subjects) representing different types of communities (2,000 families from urban, 2,000 families from suburban and 3,000 families from rural communities). All members of these samples were personally interviewed at home. Full clinical assessment and special investigations required for the diagnosis of different types of chorea, dystonia and athetosis were carried out in Assiut University Hospital. The prevalence rate for rheumatic chorea was 62/100,000 population and it was significantly higher (p < 0.01) among rural than urban and suburban populations, whereas Huntington's chorea had a prevalence rate of 21/100,000 with no significant difference between different areas studied (urban, suburban and rural). The other two common types of chorea were reported with prevalence rates of 12/100,000 for the encephalitic type and 17/100,000 for the atherosclerotic type. No single case of generalized dystonia was recorded and all cases were of the focal type of dystonia with a prevalence rate of 26/100,000 population. No significant differences were recorded between the different areas studied (urban, suburban and rural).(ABSTRACT TRUNCATED AT 250 WORDS)
不自主运动起源于神经系统的不同部位。运动的特征取决于病变部位和病理变化类型。患者出现一种以上类型的不自主运动可导致运动障碍的正确分类出现混淆和困难，进而导致鉴别诊断和适当治疗方面的问题。本研究旨在评估上埃及代表性社区阿斯尤特舞蹈症、肌张力障碍、手足徐动症和偏身投掷症的患病率，并研究其病因。本研究对代表不同类型社区的7000个家庭（42000名受试者）进行了调查（2000个家庭来自城市，2000个家庭来自郊区，3000个家庭来自农村社区）。这些样本的所有成员均在家中接受了个人访谈。在阿斯尤特大学医院对不同类型的舞蹈症、肌张力障碍和手足徐动症进行诊断所需的全面临床评估和特殊检查。风湿性舞蹈症的患病率为62/100000，农村地区显著高于城市和郊区人口（p<0.01），而亨廷顿舞蹈症的患病率为21/100000，在所研究的不同地区（城市、郊区和农村）之间无显著差异。另外两种常见的舞蹈症类型，脑炎型患病率为12/100000，动脉粥样硬化型患病率为17/100000。未记录到全身性肌张力障碍的病例，所有病例均为局灶性肌张力障碍，患病率为26/100000。在所研究的不同地区（城市、郊区和农村）之间未记录到显著差异。（摘要截断于250字）
