Bachofen H, Gurtner H P, Salzmann C
Schweiz Med Wochenschr. 1976 Nov 6;106(45):1551-3.
Ethyl ether dissolved in saline has been used as an indicator for measuring cardiac output in patients with various congenital and acquired valvular heart diseases without shunts. The solution was infused at a constant rate into the superior vena cava. By means of a simultaneous rebreathing maneuver it was possible to determine the ether concentration of the mixed venous blood and hence the dilution factor. Comparative measurements with the direct Fick method revealed a satisfactory accuracy of the ether dilution method (r = 0.94), which does not require sampling and analysis of mixed venous and arterial blood.
溶解于生理盐水中的乙醚已被用作测量各种无分流的先天性和后天性瓣膜性心脏病患者心输出量的指标。该溶液以恒定速率注入上腔静脉。通过同步重复呼吸操作,可以测定混合静脉血中的乙醚浓度,从而确定稀释因子。与直接菲克法的对比测量显示,乙醚稀释法具有令人满意的准确性(r = 0.94),该方法无需采集和分析混合静脉血和动脉血。