Astorri E, Ridolo E, Dall'Aglio P P, Gavaruzzi G, Contini G A, Albertini D
Cattedra di Cardiologia, Università degli Studi di Parma.
Minerva Cardioangiol. 1994 Jul-Aug;42(7-8):373-7.
We present the clinical case of a 26-year-old woman, suffering systemic lupus erythematosus for 15 years, who suddenly had coronary heart disease with angina pectoris on mild effort. Thallium 201 exercise test demonstrated clearcut anteroseptal and apical perfusion defects, whereas repeated echocardiography showed a hypokinetic anteroseptal segment; ECG also reported new Q wave in lead V4. After stronger corticosteroid and immunosuppressive treatment, angina pectoris attenuated and perfusion defects disappeared within few months. We hypothesize a coronary artery vasculitis in the course of systemic lupus erythematosus, probably associated with early coronary artery atherosclerosis.
我们报告了一例临床病例，患者为一名26岁女性，患系统性红斑狼疮15年，在轻度活动时突然发生冠心病并伴有心绞痛。铊201运动试验显示前间壁和心尖部有明确的灌注缺损，而多次超声心动图显示前间壁节段运动减弱；心电图也报告V4导联出现新的Q波。经过更强效的皮质类固醇和免疫抑制治疗后，心绞痛减轻，灌注缺损在数月内消失。我们推测在系统性红斑狼疮病程中存在冠状动脉血管炎，可能与早期冠状动脉粥样硬化有关。
